Designer buying a desktop PC - what are some good specs to look out for in 2010?

I’m planning on purchasing or building a new desktop next month, and curious to hear from other designers what sort of specs I should currently be on the lookout for. I’m a web and print designer - with a fair amount of illustration work to boot throughout the rest of the 2010.

A little bit of information on my usage:

* Heavy Photoshop, Illustrator and InDesign user (all CS4)
* Light Flash CS4 user.
* Heavy browser testing - (FF, Opera, Safari, IE7 & IE8, and Chrome all up and running at the same time along with Photoshop and Dreamweaver.)
* Buying a new Wacom tablet for complex illustration / painting work.
* Will be adding a blog to my site and considering recording podcasts, video casts, or screencasts to it. No experience with any of those - but want to make sure the desktop is ready.

In summary, I have the entire CS4 Master Suite - but pretty much only use PS, ID, Illustrator, DW and a little Flash. Never had a tablet before so I want to make sure I’m ready to paint and draw to my hearts content. Any general suggestions on what i should be on the lookout for in a new desktop? - how much Ram, graphics cards, processors, monitors, etc.

I’d also be curious about monitors. I’ve seen a few people with HUGE monitors - that look like flat-screen TVs. I’ve also seen others using 2 or more large - but more standard size monitors in their workspace. Obviously at some point how much screen realestate i get comes down to what i can afford - but i’m curious to hear what others like, or dislike.

THANKS for ANY input!!