I got seven script error warnings, five due to curvyCorners and two were cufon, when using IE Tester. So check the scripts documentation on how they should be used.
Page is broken in IE6, slightly damaged in IE7 and nearly okay in IE8.
Just had a look at web stats for one of my sites, registering 3.9% on IE6 :D, so we may be there soon. (but other sites say 6 - 8% IE6)
EDIT I get even more script warnings on the portfolio page - visitors are just going to leave in frustration with all these error messages.