There are changes you can set on your monitor and in your OS, however changing display settings in a program like Adobe stuff might not be possible. It seems to me you may need to send a mail to Adobe to ask them. Since things like changing contrast and default colours and font sizes are typical in applications built for the visually impaired, I can see these being problems for design applications: the user needs to be able to see the intended displayed colour, contrast, and size on the canvas. But it's possible things like tools and buttons can be improved.
You may also be able to change your system fonts and colours in your OS. Desktop applications are generally supposed to be affected by these settings, and Adobe stuff are desktop applications, so it's possible playing with those settings can improve your program.