No Leading or Trailing Padding And No Combining Of Adjacent Paddings

If you are setting the font sizes in your content with rems, then negating word-spacing by assigning {font-size:0} to the parent container of the inline-block elements will work in modern browsers.

There is a lengthy discussion in this thread from last year that explores several interesting techniques for negating the white-space between inline elements, including what works and what doesn’t. It’s well worth the read.