Firstly, I would have to say I’m completely puzzled by your suggestion that the design of a site should depend on the domain name. The design of the site should depend on the content.
I’m not an affiliate marketer, and again, I don’t really see what that has to do with a design review, but here are my first thought on the site.
The layout is OK. Nothing special, but easy enough to navigate.
The content is a problem.
On the home page, three images which are purely decorative all have the alt text “smiley face”, while the page header image, which includes text has no alt text at all. That image has also been poorly edited and the aspect changed, as the woman on the left is oddly elongated. I didn’t look closely at the other pages, but they seem to be similar in this respect.
But the real problem lies with the text. It has either been written by somebody with a poor grasp of English, or it has been translated by some automated system, because much of it makes little sense.
It is in our considerations, you are persisted, assisted, forced and given strong suggestions. We do it to your need or craze on being prettyby getting rid of your excessive weight which is sabotaging your figure.
That is pretty incomprehensible, but worse, it comes from the “about us” page. I would expect that page to give information about the site, its owner(s) and contact details. It doesn’t. It gives more “information” about the scheme it is trying to promote.
I’m sorry, but as it stands, the whole site looks to me more like a scam than a serious business site.