How can happen that 100x100 pixels image has more than 100 Kb size?

Thank you for all your responses! I use Photoshop to create thumbnails. It’s thumbnails for the catalogue, so I need to create several thumbnails at a time . I have an action and a droplet to automate the process. But only some of images give thumbnails with considerably bigger size.
I think I should try to review my Photoshop action and make save for web.
I can’t give an example now. The described problem happens at work, on Mac. At home I , on my PC computer I didn’t have that problem. And I didn’t have the same images.
Anyway, If I still have an issue with thumbnail size I’ll give an example here.
Thanks again!

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