If I could find no commonality between the exceptional cases you reported, the first place I’d look is how the public files are accessing the include directory.
Is /adsense a child of the include directory named in your php ini file, or is it set per directory (.htaccess), per server instance (httpd.conf) or per script and relying on some magic constant appearing from somewhere.
That ironed out and discounted, and if you are including per script and the inclusion of /adsense files is dependent upon some conditional assessment, then make sure those conditions are bomb-proof (preferring === to == for example).
These are the things I would tend to look at first.