I've been using InkScape and Gimp for some time now. I use them for graphic design elements for web design projects, and for design layouts & mock-ups.
I hand code each project in HTML5/CSS3/PHP, and have taken to using CSS3 effects (eg. gradients, box-shadows, text-shadows, etc) over images where possible, so have no need for HTML/CSS code generation.
As I'm starting to collaborate more with other agencies, graphic designers and developers, I'm beginning to wonder if I need to bite the bullet and use the 'industry standard' tools - Adobe Illustrator, Fireworks & Photoshop.
So rather than ask which is better, I'd like to ask what you actually use yourselves?
3) InkScape + Gimp
4) Adobe Photoshop
5) Adobe Illustrator
6) Adobe Fireworks
7) Adobe Photoshop + Illustrator
8) Adobe Photoshop + Illustrator + Fireworks
9) Adobe Photoshop + Fireworks
10) Adobe Illustrator + Fireworks
11) Adobe InDesign
12) In browser design & development