Reading Responsive Web Design by Ethan Marcotte right now and it is a very fascinating book. Shapes the way I am looking at building websites now and a more fluid and adaptive sense to allow for universal access on every mobile and desktop device. What I find interesting is that it is a "mobile first" design approach, meaning the mobile framework can often times be built first for a robust and responsive web design.

Does anybody have any recommendations on a good responsive design framework to work with? And are there better alternatives to respond.js for IE6 or is this the best @media-query fix to go with? I think those are the only questions that I have right now but I may have more as time goes on.