I'm with Ralph and I've never been keen on grids because you end up with masses of css like this:
Code:
/* Base Grid */
.container .one.column { width: 40px; }
.container .two.columns { width: 100px; }
.container .three.columns { width: 160px; }
.container .four.columns { width: 220px; }
.container .five.columns { width: 280px; }
.container .six.columns { width: 340px; }
.container .seven.columns { width: 400px; }
.container .eight.columns { width: 460px; }
.container .nine.columns { width: 520px; }
.container .ten.columns { width: 580px; }
.container .eleven.columns { width: 640px; }
.container .twelve.columns { width: 700px; }
.container .thirteen.columns { width: 760px; }
.container .fourteen.columns { width: 820px; }
.container .fifteen.columns { width: 880px; }
.container .sixteen.columns { width: 940px; }
.container .one-third.column { width: 300px; }
.container .two-thirds.column { width: 620px; }
When in effect you only need the one rule and not rules for every occurrence that you will never need.
Of course you could pick and choose what you need form the rules but then you may have well done it yourself to start with. It's useful to look at the code and see how things are laid out and how the media queries work and what limits work best but do you really need all that code for every site? I doubt it.
Some people love grids of course so make your own mind up
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