This has been a discussion on other sites before, and surely on this one as well, but when I search I am left with more results than I can possibly browse right now. I have read a couple of articles on this matter, but with that said, they are also severely outdated. So, I was hoping not only could discussion be started on this topic, but also fresh articles and links made available as well.

One template layout, perhaps loosely based on the grid system (or not, this is about discussing akll possible solutions), allowing for full (horizontal, vertical, and every which-a-way) control over elements with css.

Or does this (tinyurl 'dot' com 'slash' onelayout) article (it is an article over at TJK Design) cover it all already? I am hoping to find what HTML is to CSS as the Sandbox is for WordPress (perhaps, slightly, maybe).