If it requires manually selecting keywords, then that would be pretty tough for a dynamic site and I probably wouldn't be interested. Vibrant is kind of like Adsense in that it looks at the page and figures out what words to go with. The click through rates and payout so far have been very good, and the total work involved for me was dropping the code in my footer... no work is a good thing. And it loads last on the page, so it shouldn't slow anything down.
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