Hi Mithos,
Welcome to the sitepoint forums.
I can't really answer your questions without looking at what you have got otherwise I would need to write a book to tell you how to do everything
The questions you are asking are basic design questions and will depend on the task in hand and therefore advice would be relevant to what you are actually doing at the time.
1) You say you have positional differences in various browsers and this is likely to be the default margin and padding that is applied to nearly all elements by default. This varies between browsers and you need to set the padding and margin explicitly on all elements you use otherwise they will be different in various browsers.
2) If you want a layout to scale with the browser window then you need so size everything in percentages and not fixed widths. Of course this does present other design problems and is not as straight forward as it sounds. Look at the 3 col layout demo thread to see how a flexible page can be constructed.
However if you have fixed elements like a graph then these obviously cannot be resized and therefore you may be better off with a fixed width.
3) That site you linked to is merely a fixed width site that is centred in the browsers window using margin:auto to center it. margin:auto applied to an element with a specified width will cause that element to be centred horizontally in the viewport. (See the faq on centering as there are other things to consider for older browsers.)
It would also be worth your while to take some time and read through all the css faq as you will run into many of the issues listed there sooner or later.
Off Topic:
droopsnoot - I bought one of first Firenza droopsnoot's when they were first made (must have been about 35 years ago). I believe mine was one of the first batch of 20 that was raced around thruxton as it came supplied with rollbars, fire extinguishers, engine cut off and full harness etc.
It was the worst car I ever owned in terms of reliability but it did look great at the time

. The gearbox was a nightmare to use and no-one could drive it but me and the exhaust fell off every time you went over a cats-eye because it was too low. The glass panels in the droopsnoot section would also fall out daily as well. The safety tyres also blew out.
However when it was working it was great and drove very well. Just though you might be interested seeing the link in your sig
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